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Gene cassette : ウィキペディア英語版 | Gene cassette A gene cassette is a type of mobile genetic element that contains a gene and a recombination site. They may exist incorporated into an integron or freely as circular DNA. Gene cassettes often carry antibiotic resistance genes. An example would be the ''kanMX'' cassette which confers kanamycin (an antibiotic) resistance upon bacteria. == Integrons == (詳細はbacteria which express and are capable of acquiring and exchanging gene cassettes. These cassettes typically carry a single gene without a promoter. The entire series of cassettes is transcribed from an adjacent promoter. The gene cassettes are speculated to be inserted and excised via a circular intermediate. This would involve recombination between short sequences found at their termini and known as 59 base elements (59-be) - which may not be 59 bases long. The 59-be are a diverse family of sequences that function as recognition sites for the site-specific integrase (enzyme responsible for integrating the gene cassette into an integron).
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Gene cassette」の詳細全文を読む
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